Started with Egypt on Prince difficulty, Continent style map, 8 major players, Quick pace.
Victorious after about 320+ turns on reaching 2050AD. All research completed. Completed all parts for getting the Science victory. Eliminated all nations except the capital of a single nation (intentionally).
Had a horrible defeat taking India, don't take it if you have conquest in mind. The unhappiness keeps on mounting.
Take Egypt and go for Pyramids asap. Now watch your workers on the fly.
Soon you'll be watching nuclear subs firing at caravels or Robots squashing pikemen