My office uses Symantec Endpoint, but I think its not suitable or cost effective for SOHO. I'd used avast for so long I'm not sure about the current status of commercial antiviruses. From what I gathered from some recent reports, Bitdefender, Eset, Avast Paid Edition, Kaspersky will serve you good.
PS: AV-Comparatives Independent Tests of Anti-Virus Software » AV-Comparatives