which type of software you use for pc tunup?

well i use CCleaner for clearing temp files & reg entries.
Along with defragler to defrag my HDD!
Also Perfect disk is good for defrag as it can defrag even system files at starup if scheduled !!

1) tuneup 2010
2) registry mechanic
3) advanced sys care pro 3
4) Ccleaner (use it rare)
5) auslogics disk defrag.